Kpekawa, Hewitt and Healey cleared for action.
Cardiff City, Ipswich Town and Queens Park Rangers respectively have given the U's permission to use the three in the Second Round clash here at the Weston Homes Community Stadium.
Fellow loanee Will Packwood won't be facing Darren Ferguson's side though, he serves a one match suspension for the red card received at MK Dons last weekend.
Boss Tony Humes reacted to the news by saying: "It's excellent news that the three of them can be used in the cup, they have all done well in their time with us so far.
"The clubs that they've come from don't have to allow them to play so I'd like to thank them for allowing us to use them.
"It's unfortunate that Will can't play but we'll get on with things without him and welcome him back when the league games come round again."