Humes' men face Middlesex side in First Round.
The game will take place on the weekend of November 7th and 8th, after this Saturday's trip to Doncaster Rovers.
The U's hosts currently sit in 17th place in the Conference South, and have former U's striker Scott McGleish amongst their number.
Ticket details for the game will follow in the next few days, with the game less than two weeks away.
at the Saver rate!Buy your tickets nowColchester United take on high-flying Coventry in their next home game as they look to push up the table.