Back injury rules out U's skipper.
U's: Cousins, Pentney, Rose, Okuonghae, Heath, Duguid, O'Toole, Morrison, Sears, Bond, Bean, Henderson, Eastman, Wilson, Massey, Wordsworth, White, Coker, Gilbey, Wright
The U's will be able to include new signing Gavin Massey in their squad however, after the new boy trained with his teammates in the second half of the week after sealing a permanent switch from Watford.
The midfield played well in the match against Pompey and it looks set to be an unchanged core to the U's team as they look to notch their first win of the season against Danny Wilson's Blades.
Kem was absent from the U's enthralling 2-2 draw with Portsmouth on Tuesday, having hurt his back and it is likely that boss John Ward will again rest him for the game against Sheffield United this weekend.
U's captain Kem Izzet is set to miss a second game in a week, as a back problem rules him out of action.